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KMID : 1035620170050020117
Allergy Asthma & Respiratory Disease
2017 Volume.5 No. 2 p.117 ~ p.120
Successful desensitization of a patient with albumin hypersensitivity
Jung So-Yoon

Choi Yun-Jung
Lee Seung-Hyun
Kang Hye-Ryun
Suh Dong-In
Abstract
There have been few cases of albumin hypersensitivity reported, and there is limited information on this condition. When a patient is anaphylactic to a certain drug and no alternative drug is available to treat the underlying condition, desensitization is a reasonable option and can be performed successfully to treat the patient. A standard 12-step, 3-solution rapid desensitization protocol allows the safe readministration of a medication after certain types of immediate hypersensitivity. However, we demonstrated that a new 10-step, 1-solution desensitization protocol using antihistamine and leukotriene receptor antagonist as premedications, which was effective and safe in a patient with hypersensitivity. We report a 13-year-old boy with Gorham-stout syndrome who was presented with newly acquired albumin anaphylaxis and successfully treated with the 10-step rapid drug desensitization protocol.
KEYWORD
Drug hypersensitivity syndrome, Anaphylaxis, Immunologic desensitization
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