KMID : 1035620170050020117
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Allergy Asthma & Respiratory Disease 2017 Volume.5 No. 2 p.117 ~ p.120
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Successful desensitization of a patient with albumin hypersensitivity
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Jung So-Yoon
Choi Yun-Jung Lee Seung-Hyun Kang Hye-Ryun Suh Dong-In
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Abstract
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There have been few cases of albumin hypersensitivity reported, and there is limited information on this condition. When a patient is anaphylactic to a certain drug and no alternative drug is available to treat the underlying condition, desensitization is a reasonable option and can be performed successfully to treat the patient. A standard 12-step, 3-solution rapid desensitization protocol allows the safe readministration of a medication after certain types of immediate hypersensitivity. However, we demonstrated that a new 10-step, 1-solution desensitization protocol using antihistamine and leukotriene receptor antagonist as premedications, which was effective and safe in a patient with hypersensitivity. We report a 13-year-old boy with Gorham-stout syndrome who was presented with newly acquired albumin anaphylaxis and successfully treated with the 10-step rapid drug desensitization protocol.
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KEYWORD
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Drug hypersensitivity syndrome, Anaphylaxis, Immunologic desensitization
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